LYMPHATIC FILARIASIS: AN IMMUNOLOGIC PERSPECTIVE

Lymphatic Filariasis: An Immunologic Perspective

Lymphatic Filariasis: An Immunologic Perspective

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Introduction: This paper provides an overview of the current immunologic research findings of lymphatic filarial worms, which affect millions of people worldwide.Objectives: This paper aims to discuss the immunologic features of lymphatic filarial worms.It also aims to highlight their potential anti-inflammatory actions and the use of anti-filarial drugs against COVID-19.Methods: A literature review was performed to obtain insights on the immunologic features of Celiac lymphatic filarial worms.Results: The CD4+ (Th2) response profile is the main defence against filarial worms.

Modulation of human immune responses are primarily mediated by parasite-secreted peptides.Lymphatic filarial worms have anti-inflammatory potentials.Drug Cable Suspension repurposing of diethylcarbamazepine, doxycycline, and ivermectin can be looked upon against COVID-19.Conclusion: Lymphatic filarial worms have several immunologic effects on host immune systems, which promote chronic infection and curtail anti-inflammatory responses.Insights in this paper can serve as a guide for the understanding of immunologic aspects of lymphatic filarial worms.

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